Raffaele Ingenito,Philip Jones,Laura Llauger Bufi,Jesus Maria Ontoria Ontoria,Rita Scarpelli
申请号：
US12922270
公开号：
US08362030B2
申请日:
2009.03.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment.
