The present disclosure relates to a breakaway coupling. A female adapter on a source side of the coupling uses a valve to prevent a flow of contents from the source when the coupling is not connected or is broken apart. A male adapter on a destination side uses a valve to prevent backflow from the destination when the female and male adapters are not coupled together. When coupled, the male adapter penetrates the valve of the female adapter, thereby allowing the flow from the source to the destination via the male and female adapters. Pressure from the flow opens the valve of the male adapter allowing the flow from the source to proceed to the destination. In the coupled state, the male and female adapters, and respective tubes, are able to rotate with respect to each other. The coupling may be used to deliver medical fluids to a patient.