Fuqiang Ruan,Thomas L. Deckwerth,Martin D. Meglasson
申请号:
US13708306
公开号:
US08974766B2
申请日:
2012.12.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents.