Benatuil, Lorenzo,Argiriadi, Maria A.,McRae, Bradford L.,Hsieh, Chung-Ming
申请号:
AU2016270640
公开号:
AU2016270640A1
申请日:
2016.05.27
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention encompasses antagonist anti-CD40 antibodies and antigen-binding portions thereof. Specifically, the invention relates to humanized anti-CD40 antibodies. In certain embodiments, antibodies of the invention neutralize human CD40 (hCD40) activity. Antibodies, or antibody portions, of the invention are useful for detecting CD40 and for inhibiting CD40 activity,