THE PRESENT INVENTION FEATURES PROCESSES OF MAKING TABLETS HAVING REDUCED INTERNAL FRACTURES. IN ONE ASPECT, THE PROCESSES COMPRISE THE STEPS OF (1) COMPRESSING A PRE-TABLETTING MATERIAL IN A DIE TO FORM A TABLET, WHERE AN INTERNAL SURFACE OF THE DIE IS LUBRICATED WITH AT LEAST ONE LUBRICANT, AND THE PRETABLETTING MATERIAL COMPRISES AT LEAST ONE THERAPEUTIC AGENT AND AT LEAST ONE PHARMACEUTICALLY ACCEPTABLE POLYMER AND (2) EJECTING SAID TABLET FROM SAID DIE. IN ANOTHER ASPECT, THE PROCESSES EMPLOY A GRANULAR OR POWDERY PRE-TABLETTING MATERIAL WHICH COMPRISES AT LEAST ONE THERAPEUTIC AGENT AND AT LEAST ONE PHARMACEUTICALLY ACCEPTABLE POLYMER, WHEREIN 90% OF THE PARTICLES IN THE PRE-TABLETTING MATERIAL ARE SMALLER THAN 400 MICROMETER.
