An objective of the present invention is to provide a capsule medicine manufacturing apparatus capable of quickly controlling an alignment position of a medicine capsule forming roller without a work time delay. The capsule medicine manufacturing apparatus comprises: a frame; a pair of medicine capsule forming rollers being rotatably coupled to the frame and having film insertion holes dented on a plate surface; a film supply unit to supply a film to the pair of medicine capsule forming rollers; a medicine supply unit to supply a medicine between the pair of medicine capsule forming rollers; and a forming roller position alignment unit to align the circumferential position of the pair of medicine capsule forming rollers to arrange the film insertion holes of the pair of medicine capsule forming rollers to correspond to each other. The medicine capsule forming roller includes: a pair of forming roller driving shafts rotatably coupled to the frame; and a forming roller body which is detachably coupled to the pair of forming roller driving shafts, and has the film insertion holes dented on a plate surface. The forming roller position alignment unit includes: a driving shaft bevel gear coupled to the other end of any one among the pair of forming roller driving shafts; a position alignment bevel gear engaged with the driving shaft bevel gear to rotate the driving shaft bevel gear; a position alignment bevel gear motor to drive the position alignment bevel gear forwards and backwards; and a bevel gear control dial to control forward/backwards drive of the position alignment bevel gear motor.본 발명은 본 발명의 캡슐약제조장치는, 프레임과; 상기 프레임에 회전가능하게 결합되며 판면에 필름삽입공이 함몰형성된 한 쌍의 약캡슐성형롤러와; 상기 한 쌍의 약캡슐성형롤러로 필름을 공급하는 필름공급부와; 상기 한 쌍의 약캡슐성형롤러 사이로 약을 공급하는 약공급부와; 상기 한 쌍의 약캡슐성형롤러의 필름삽입공이 서로 대응되게 배치되도록 상기 한 쌍의 약캡슐성형롤러의 원주방향 위치를 정렬하는 성형롤러위치정렬부를 포함하며, 상기 약캡슐성형롤러는, 상기 프레임에 회전가능하게 결합된 한 쌍의 성형롤러구동축과; 상기 한 쌍의 성형롤러구동축에 착탈가능하게 결합되며 판면에 상기 필름삽입공이 함몰형성된 성형롤러본체를 포함하며, 상기 성형롤러위치정렬부는, 상기 한 쌍의 성형롤러구동축 중 어느하나의 타단부