Thermo-sensitive, mucoadhesive or dermoadhesive, and penetration-enhancing formulations for topical delivery of therapeutics

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专利权人:

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION; INC.

发明人:

Stephen I-Hong Hsu

申请号：

US14739334

公开号：

US09339548B2

申请日:

2015.06.15

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides thermo-sensitive, mucoadhesive biopolymer formulations that enhance the penetration of therapeutics across the skin or mucosal surfaces. In a preferred embodiment, the biopolymer formulation comprises co-polymer of poloxamer 188 and propylene glycol, laurocapram and, optionally, one or more therapeutic agents. Also provided are uses of the biopolymer formulations for topical therapy of cancer including cervical cancer.

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