Thermo-sensitive, mucoadhesive or dermoadhesive, and penetration-enhancing formulations for topical delivery of therapeutics

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专利权人:

University of Florida Research Foundation; Inc.

发明人:

Hsu, Stephen I-Hong

申请号：

AU2012236493

公开号：

AU2012236493A1

申请日:

2012.03.29

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention provides thermo-sensitive, mucoadhesive biopolymer formulations that enhance the penetration of therapeutics across the skin or mucosal surfaces. In a preferred embodiment, the biopoiymer formulation comprises co-polymer of poloxamer 188 and propylene glycol, laurocapram and, optionally, one or more therapeutic agents. Also provided are uses of the biopoiymer formulations for topical therapy of cancer including cervical cancer.

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