A multi-stage separation heat-exchange type drying system is provided. A plurality of first heat exchange blocks of the first main body are installed to be spaced from each other at a predetermined interval, and first vortex generating blocks are installed between the first heat exchange blocks. Also, a plurality of second heat exchange blocks of the second main body are installed to be spaced apart from each other at a predetermined interval, and second vortex generating blocks are installed between the second heat exchange blocks. The heat exchange occurs in a manner that the first heat exchange blocks and the second heat exchange blocks corresponding to each other, positioned up and down, exchange a heat medium therebetween.