A method for establishing a chronic ocular hypertension animal model. The method comprises: creating a glaucoma animal model having an elevated ocular pressure and damaged optic nerves by surgically inserting a material to block off an outflow pathway for an aqueous humor, such that the elevated ocular pressure is maintained and stabilized, and can be obtained and manipulated more easily. The obtained model has advantages such as a stable elevation and small fluctuations of the ocular pressure, the high ocular pressure can be maintained for a long time and the target ocular pressure can be controlled. A chronic ocular hypertension animal model can be made by using the method, and an ocular pressure thereof can be adjusted and controlled according to different degrees of blockage of the Schlemms canal the blockage of the Schlemms canal can be completed by selecting fiber ducts of different specifications and sizes on the basis of different diameters of the Schlemms canals in different types of animals, thereby generating chronic ocular hypertension animal models for multiple types of animals. The method enables the establishment of clinically compatible model-making animals and model-making methods for research into the mechanism of chronic ocular hypertension glaucoma, and provides a foundation for the mechanism of optic nerve damage in chronic glaucoma.La présente invention concerne un procédé de mise en place dun modèle animal dhypertension oculaire chronique. Le procédé comprend : la création dun modèle de glaucome chez lanimal présentant une pression oculaire élevée et des nerfs optiques détériorés en introduisant chirurgicalement un matériau en vue de bloquer un trajet dévacuation dune humeur aqueuse, de manière que la pression oculaire élevée soit maintenue et stabilisée, et puisse être obtenue et manipulée plus facilement. Le modèle obtenu présente les avantages tels quune élévation stable et de petites fluctuations de la pression oculaire, la pression oculai
