Methods using an osteopenia animal model

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专利权人:

发明人:

申请号：

EP11169483.2

公开号：

EP2389803A3

申请日:

2007.10.11

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides a method for producing an osteopenia animal model by RANKL administration and an osteopenia animal model.Also, a method for producing an osteopenia animal model, comprising administering, soluble RANKL or a fused protein of soluble RANKL with an epitope tag to a non-human animal so as to promote in vivo osteoclast differentiation and activation in the non-human animal, and an osteopenia animal model produced by the method are provided.

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