As for this invention, mamegurichiriza (Glycyrrhiza) being attached plant, and mamegurichiriza (Glycyrrhiza) the water extraction residue of the being attached plant at least in each case extracting processing with the organic solvent, containing the oil soluble licorice extract which can, it becomes, hyaluronidase active obstruction action and hekisosaminidaze separation control action (namely, histamine separation control action), it is the anti- inflammation medicine which at least possesses the action of 1 where it is selected from blood platelet cohesion control action and phospholipase A2 active obstruction action kinds.本発明は、マメ科グリチリザ(Glycyrrhiza)属植物、及びマメ科グリチリザ(Glycyrrhiza)属植物の水抽出残渣の少なくともいずれかを有機溶媒で抽出処理して得られる油溶性甘草抽出物を含有してなり、ヒアルロニダーゼ活性阻害作用、ヘキソサミニダーゼ遊離抑制作用(即ち、ヒスタミン遊離抑制作用)、血小板凝集抑制作用及びホスホリパーゼA2活性阻害作用から選択される少なくとも1種の作用を有する抗炎症剤である。
