Smiti V. GUPTA,Pramod KHOSLA,Xiangming JI,Ravigadevi SAMBANTHAMURTHI,Yew Ai TAN
申请号:
US15400556
公开号:
US20170151304A1
申请日:
2017.01.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Present invention relates to a composition to inhibit cancer cell proliferation, wherein said composition comprises oil palm extracts. The composition is useful for prevention of pancreatic cancer by inhibiting clonogenicity, inducing apoptosis, regulating gene expression, inducing anti-invasive effect, and induces cell cycle arrest in S phase. Present invention also discloses a composition that inhibits NF-κB activity and reduces cell invasion, cell migration and metastasis. Present invention further discloses the use of therapeutically effective amount of a composition in inhibiting the growth of pancreatic cancer.