The present invention discloses a wearable physiological monitoring device for detecting a users mental state, which includes an eyeglass structure having two temples and a frame to be mounted on the users head through ears and nose of the user a first electrode disposed on the frame of the eyeglass structure a second electrode disposed on one temple of the eyeglass structure and a physiological signal acquisition circuit to obtain EEG signal and EOG (Electrooculography) signal through the first electrode and second electrode, wherein the first electrode is involved in the acquisition of EEG signal, and the second electrode is involved in the acquisition of EOG signal, and the EEG signal and EOG signal are used to obtain the mental state of the user.本發明揭示一種穿戴式生理監測裝置,用以偵測一使用者的精神狀態,其包括具有二鏡腳以及一鏡框的眼鏡結構,通過使用者的耳廓以及鼻子而設置於使用者的頭上,設置於該眼鏡結構的該鏡框上的一第一電極,設置於該眼鏡結構的一鏡腳上的一第二電極,以及一生理訊號擷取電路,通過該第一電極以及該第二電極取得腦電訊號以及眼電訊號,其中,該第一電極參與該腦電訊號的取得,以及該第二電極參與該眼電訊號的取得,並且,該腦電訊號以及該眼電訊號用以得出該使用者的一精神狀態。10‧‧‧電極12‧‧‧電極