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IDENTITY MARKERS
专利权人:
Jeffrey Keeler Teumer;Vladimir Mastyugin;Agatha Zawadzka;Jizeng Qiao
发明人:
Jeffrey Keeler Teumer,Vladimir Mastyugin,Jizeng Qiao,Agatha Zawadzka
申请号:
US13386456
公开号:
US20120128632A1
申请日:
2010.07.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods for identifying trichogenic dermal cells, including dermal papilla cells and dermal sheath cells, capable of inducing hair follicle formation when injected into skin are provided. It has been discovered that EGF latrophilin and seven transmembrane domain-containing protein 1 (ELTD1). Transmembrane Protein 108 (TMEM1 08), Hyaluronan and proteoglycan link protein 1 (HAPLN1) are biomarkers that can be used to detect, identify, and distinguish trichogenic dermal cells, i.e., that are able to induce hair follicle formation, from other skin cells. Populations of skin cells enriched with trichogenic dermal cells can be produced by selecting for and enriching for dermal cells that express ELTD1, TMEM1 08, HAPLN1, or a combination thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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