The invention relates to granules of an active substance with a double taste-masking technique, wherein the double taste-masking technique is achieved by a thermofusible compound selected from waxes, hydrogenated vegetable oils, fatty acids, mono-, di- and triesters of fatty acids and glycerol, triglycerides, glycerides, polyoxylglycerides, fatty alcohols, and the mixtures thereof, and a soluble thermoplastic polymer with a pH lower than or equal to 5. The invention also relates to the method for producing said granules and to the orodispersible tablets containing said coated granules.