Gordana Vunjak-Novakovic,Joshua Sonett,John ONeill,Matthew Bacchetta,Donald O. Freytes,Gopal Singh,Scott A. Kanner
申请号：
US14245387
公开号：
US09888680B2
申请日:
2014.04.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The vasculature of a donor lung is perfused with a lung preserving fluid to preserve its structure. At the same time, a decellularization fluid is perfused through the airways, which strips away donor cells. The decellularized region is then seeded with pulmonary cells of the transplant recipient, which regenerate the lung. The pulmonary cells may be derived from stem cells, and the decellularization can be targeted to reduce the quantity of cells required.
