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EML4-ALK FUSION GENE
专利权人:
发明人:
HIROYUKI MANO,Sadao Kuromitsu,Nobuaki Shindo,Takatoshi Soga,Takashi Furutani
申请号:
US15810918
公开号:
US20180066266A1
申请日:
2017.11.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene
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