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PRIPRAVCI I POSTUPCI ZA INHIBICIJU EKSPRESIJE GENA ALAS1
专利权人:
Alnylam Pharmaceuticals, Inc.;Icahn School of Medicine at Mount Sinai
发明人:
Bettencourt, Brian,Fitzgerald, Kevin,Querbes, William,Desnick, Robert J.,Yasuda, Makiko
申请号:
HRP20200822
公开号:
HRP20200822T1
申请日:
2020.05.21
申请国别(地区):
HR
年份:
2020
代理人:
摘要:
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting expression of ALAS1, wherein said dsRNA comprises a sense strand and an antisense strand, the antisense strand comprising a region of complementarity to an ALAS1 RNA transcript, which antisense strand comprises at least 22 contiguous nucleotides from the antisense sequence of UAAGAUGAGACACUCUUUCUGGU (SEQ ID NO: 4153) or UAAGAUGAGACACUCTUUCUGGU (SEQ ID NO: 4154).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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