您的位置: 首页 > 农业专利 > 详情页

HYDROPHILIC SELF IMMOLATIVE LINKERS AND CONJUGATES THEREOF
专利权人:
发明人:
LIN RONG-HWA,LIN SHIH-YAO,HSIEH YU-CHI,HUANG CHIU-CHEN
申请号:
IN5884/DELNP/2015
公开号:
IN2015DN05884A
申请日:
2015.07.04
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present disclosure provides compounds with a hydrophilic self immolative linker which is cleavable under appropriate conditions and incorporates a hydrophilic group to provide better solubility of the compound. The compounds of the present disclosure comprise a drug moiety a targeting moiety capable of targeting a selected cell population and a linker which contains an acyl unit an optional spacer unit for providing distance between the drug moiety and the targeting moiety a peptide linker which can be cleavable under appropriate conditions a hydrophilic self immolative linker and an optional second self immolative spacer or cyclization self elimination linker.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充