The present invention provides a kind of composition, it includes buffer and include by 5 -AGCAGAGUACACACAGCAUAUACC-P-GGUAUAUGCUGUGUGUACUCUGCUUC-P- G-3 (SEQ ID NO:1) indicate nucleotide sequence (in the sequence, P indicate by specification (I) indicate proline derivative connexon) single stranded nucleic acid molecule, wherein the composition is characterized in that (a) described composition is the form of solution at normal temperature, (b) at 25 DEG C, the content of the nucleic acid molecules after the lower preservation of relative humidity 60% 4 weeks is 80% or more relative to the content saved when starting.