PROBLEM TO BE SOLVED: To provide a skin external preparation which aims at utilizing a plant extract ingredients having antioxidative property, keratinization/differentiation promoting property, ECM production promoting property, and anti-aging effect, which can be especially novel active ingredients of the skin external preparation, and takes a required effect.SOLUTION: The skin external preparation contains 0.000001 to 20 wt.% of an extract of cultured cells of Potentilla miyabei in the family Rosaceae or Antennaria dioica in the family Asteraceae as active ingredients of antioxidative property, keratinization/differentiation promoting property, ECM production promoting property, and anti-aging.SELECTED DRAWING: None【課題】特に皮膚外用剤の新規有効成分と成り得る抗酸化性、角化・分化促進性、ECM産生促進性、抗老化効果を有する植物抽出成分の利用を図り、所要効果を奏する皮膚外用剤を提供する。【解決手段】バラ科キジムシロ属のメアカンキンバイ（Potentilla miyabei）またはキク科エゾノチチコグサ属のエゾノチチコグサ（Antennaria dioica）の培養細胞の抽出物を、抗酸化性、角化・分化促進性、ECM産生促進性、抗老化の有効成分として０．０００００１～２０重量％含有する皮膚外用剤とする。【選択図】なし
