Provided is a super-paramagnetic nanoparticle comprising: inorganic matters an amphipathic polymer formed on the surface of the nanoparticle and paclitaxel, wherein the amphipathic polymer is represented by chemical formula 1. According to the present invention, a super-paramagnetic nanoparticle with uniform size while being combined with an amphipathic polymer can be manufactured in a core-shell form.COPYRIGHT KIPO 2016본 발명은 무기물 및 상기 나노입자의 표면에 형성된 양친매성 고분자 물질 및 파클리탁셀을 포함하되, 상기 양친매성 고분자 물질은 [화학식 1]로 표시되는 화합물을 포함하는 초상자성 나노입자를 제공한다. [화학식 1]