LYSENKO SERGEJ ALEKSANDROVICH,Лысенко Сергей Александрович,KUGEJKO MIKHAIL MIKHAJLOVICH,Кугейко Михаил Михайлович,LISENKOVA ALLA MUSTAFOVNA,Лисенкова Алла Мустафовна
申请号:
RU2012154031/14
公开号:
RU0002521838C1
申请日:
2012.12.13
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
FIELD: medicine.SUBSTANCE: group of inventions refers to medical instrument engineering. Skin and a calibration sample are exposed to optical radiation in at least Nλ≥3 narrow or wide spectral regions Λk (k=1,…,N). Signals emitted by the skin and calibration sample are recorded with an activated and de-activated radiation emitter. Diffusion reflection factors R(Λk) are derived from the relation R(Λk)=RstdV(Λk)−v(Λk)Vstd(Λk)−vstd(Λk), wherein Rstd is a diffusion reflection factor of the calibration sample in the spectral regions Λk ν(Λk), νstd(Λk) are the signals emitted by the skin and calibration sample in the spectral regions Λk with the de-activated radiation emitter, V(Λk), Vstd(Λk) are the signals reflected from the skin and calibration sample in the spectral regions Λk with the activated radiation emitter. A penetration depth of light into the skin is determined by analytic expressions relating the spectral penetration depths of light R(Λk), or with projections R(Λk) on a space from proper vectors of a co-variation matrix R(Λk). A device comprises a wide-band light emitter, a receiving fibre optic cable and a photodetector, a monochromator, two linear polarisers, a calibration sample, and a focusing device. The photodetector is presented on the basis of a charge coupled device matrix an input of which is connected through an output of the second linear polariser receiving the emission from skin and calibration sample. An axis of the second polariser is perpendicular to an axis of the first one. An output of the photodetector is connected to a unit for recording and processing the signals from the skin and calibration sample.EFFECT: group of inventions enables providing more accurate determination of the depth penetration of light into the skin by eliminating the use of a priori information of an object being tested, the effect of a spread of instrumental constants of the reflected signal recording system, eliminating a contribution of the emission reflected f