A durable anti-mold packet comprises a holding pouch (10), an absorption material (25) and an anti-mold evaporation substance (20). The holding pouch (10) has an upper edge (12), a lower edge (13), a left edge (14) and a right edge (15). The left edge (14) and right edge (15) are folded and overlapped to form a housing space (16) and an overlapped seam edge (17). The upper edge (12) and lower edge (13) are pressed and sealed. The overlapped seam edge (17) is partially pressed and sealed to form an evaporation vent (18) communicating with the exterior. The anti-mold evaporation substance (20) is coated onto the absorption material (25) which is held in the housing space (16). Therefore a greater amount of the anti-mold evaporation substance (20) can be absorbed by the absorption material (25) and the anti-mold evaporation substance (20) can be slowly released from the absorption material (25) to increase use duration of the anti-mold packet and provide anti-mold effect for a longer period to meet use requirements.