Docket No.: EOS.004US PATENT Disclosed herein are compositions comprising a targeted corrole nanoparticle; and an acceptable excipient. Also disclosed are compositions comprising a targeted corrole nanoparticle; and an acceptable carrier. Further, disclosed herein are methods of imaging a condition in a subject, comprising providing a composition comprising a targeted corrole nanoparticle; administering an effective amount of the targeted corrole nanoparticle to the subject; and imaging the condition in the subject. In addition, disclosed herein are methods of treating cancer in a subject, comprising providing a composition comprising a targeted corrole nanoparticle; and administering a therapeutically effective dosage of the targeted corrole nanoparticle to the subject. - 16 - Figure 2. r __ __ __ __Ar' Ar + Ar HerMn HO3s HerPBK10 SO3 H S2Mn Figure 2. Assembly of HerMn. Figure 3. A a 5 -.- HerMn B C 4 HerPBKIO 3- Saline ~E 3 z 0 0 z n 0 5 10 15 20 25 Saline HerMn Time (days after treatment) Da 30