The invention discloses a kind of Wound-surface negative pressure synthetic therapy equipments, it includes the medical dressing being covered on human body wound tissue, it is covered on above medical dressing, medical transparent pad pasting for wound closure region, drainage sucking disc at medical transparent pad pasting top-open is set, the drainage system being connected by drainage tube with drainage sucking disc liquid outlet, respectively by being provided with that the joint delivery pipe of four-way connection is connected with the joint input mouth of drainage sucking disc to trophic system, oxygen system and ozonation system, and for adjusting control drainage system, the main circuit board run to trophic system and oxygen system The present apparatus not only can be suitably used for negative pressure drainage therapy, but also can be suitably used for oxygen therapy, ozone therapy and local alimentotheray, can accelerate the healing of the surface of a wound, control infection, reduce complication, promotion functions recovery, it not only can be shortened treatment time, medical expense is reduced, and easy to operate, it is easy to use.