SYSTEMS WITH CONTROL MECHANISM FOR NEGATIVE PRESSURE AND POSITIVE PRESSURE FOR OPTIMIZATION OF VENTILATION, CENTRAL HEMODYNAMICS, AND VITAL ORGAN PERFUSION
An intelligent control system for controlling a patient ventilation apparatus having at least negative end expiratory pressure ventilation (NEEP) system. The controller accepts signals from one or more physiological parameter sensors, compares data received from those sensors to target values stored in a memory, and either recommends changes to the NEEP or signals the NEEP to change or maintain certain settings, such as level and frequency. A positive end pressure ventilation system may be further employed with the intelligent control system, such that, based on data received from the physiological sensors, the intelligent control system can be used to deliver optimal levels of negative pressure ventilation and positive pressure ventilation, and promote weaning of a patient off the ventilators. The intelligent control system may also be used with an external pressure oscillatory device.