Modulation of granulosa cell apoptosis

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专利权人:

发明人:

申请号：

EP10004342.1

公开号：

EP2228070B1

申请日:

2006.07.18

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to a culture medium for an oocyte and/or an embryo, the medium including either or both of (i) GDF-9 or a variant thereof and (ii) an agent that increases the activity of a GDF-9 dependent signalling pathway in one or more of an oocyte, a cumulus cell associated with an oocyte, and an embryo and to methods using such culture medium.

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