Antibodies against domains of laminin-332

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专利权人:

Karl Tryggvason

发明人:

Karl Tryggvason,Sirpa Anne Kristiina Salo

申请号：

US13060358

公开号：

US08545845B2

申请日:

2009.06.18

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Antibodies against various domains of laminin-332 are discussed herein. The antibodies reduce the adhesion and matrix binding properties of laminin-332, inhibiting tumor growth and metastasis in vivo. Pharmaceutical compositions and methods of using the antibodies for diagnostic, prophylactic, and/or therapeutic purposes are disclosed.

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