ANTICORPS ANTI-FGFR2IIIB NON FUCOSILÉS

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专利权人:

Five Prime Therapeutics; Inc.

发明人:

申请号：

EP19151147.6

公开号：

EP3708583A1

申请日:

2014.07.31

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present disclosure relates to afucosylated anti FGFR-III2b antibody constructs, their production and and their uses as pharmaceuticals. The fucosylation site is located at Asn 297, e.g on the CH2 domain of the antibody, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

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