Агапов Игорь Иванович (RU),Мойсенович Михаил Михайлович (RU)
申请号：
RU2013132609/15
公开号：
RU2013132609A
申请日:
2013.07.15
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A process for producing biodegradable products on the basis of silk fibers, comprising the steps of: a) placing a silk thread turns of the first layer to form so that the filaments come into contact with each other but do not overlap b) treating the precursor obtained in step a) with a solution of fibroin silk in 90% formic acid with the addition of lithium chloride c) drying the product of step b) intermediate product d) stacking the second layer of silk filaments at an angle 15-90 ° to the first layer, observing the following relation: (thickness of the yarn) ≤ distance between the yarns ≤ (10- times with yarn thickness) e) laying a third layer similar to the first f) processing the precursor solution of silk fibroin in 90% formic acid with the addition of lithium chloride g) drying the resulting product h) treatment obtained in step g) etanolom.2 products. The method of claim 1, wherein the silk fibers are selected from the group: cocoon thread, silk untwisted yarn, twisted silk yarn fibroin from newly polymerized shelka.3 solution. A method according to claim 1 comprising the multiple repetition ag.4 steps. The method of claim 1, wherein lithium chloride is added at a concentration of 70 mg / ml.5. A method according to claim 1, wherein the amount of lithium chloride is 10 wt.%. 6. The method of claim 1 wherein the yarn thickness is 10-100 mkm.7. A method according to claim 6, wherein the silk yarn has a rectangular section with a thread thickness of 10-100 microns and a width of 150-500 mkm.8 silk thread. Biodegradable articles based on silk fibers produced by the method according to any one pp.1-7.9. The use of biodegradable articles based on silk fiber according to claim 8, obtained by the method according to any one of claims 1-7 as biodegradable and bioresorbable implant for reconstruction of defects and function t1. Способ получения биодеградируемого изделия на основе шелковых волокон, включающий стадии:a) укладки витков шелковой нити первого слоя на фо
