A composition comprising compounds isolated from the extract of pine tree leaf for the prevention and treatment of cancer diseases and inhibition of HPV
The present invention relates to a composition comprising a compound isolated from pine leaf extract as an active ingredient. Specifically, the compound of the present invention inhibits human papillomavirus (HPV) and inhibits cervical cancer and laryngeal cancer But also cytotoxicity against cancer cell lines such as colon cancer and cervical cancer has been confirmed. As a result, a strong anticancer activity has been confirmed and thus it can be usefully used in pharmaceutical compositions and health functional foods for prevention and treatment of various cancer diseases .본 발명은 솔잎 추출물로부터 분리된 화합물을 유효성분으로 함유하는 조성물에 관한 것으로, 구체적으로 본 발명의 화합물은 인체 파필로마바이러스(human papillomavirus, HPV)를 억제하여 상기 바이러스 감염으로 기인한 자궁경부암 및 후두암을 억제할 뿐만 아니라, 결장암, 자궁경부암 등의 암세포주에 대한 세포독성을 확인한 결과 강력한 항암활성을 확인함으로써, 각종 암질환의 예방 및 치료를 위한 약학조성물 및 건강기능식품에 유용하게 이용될 수 있다.
