Enhancement of transport of therapeutic molecules across the blood brain barrier

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专利权人:

BIOGEN MA INC.

发明人:

FARRINGTON GRAHAM K.,SISK WILLIAM

申请号：

NZ62662013

公开号：

NZ626620A

申请日:

2013.01.10

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed is a binding molecule comprising at least one pharmacologically active agent and at least one binding site that binds to TMEM30A, wherein the at least one binding site that binds to TMEM30A is fused (i) directly or (ii) via an intervening amino acid sequence to the N-terminus of an Fc moiety. Also disclosed is the use of such a binding molecule in the manufacture of a medicament for treatment of a neurological disorder.

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中国工程科技知识中心

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http://www.ckcest.cn/home/