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Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
专利权人:
发明人:
Samuel J. Danishefsky,Jennifer R. Allen,Govindaswami Ragupathi,Philip O. Livingston,Lawrence Williams
申请号:
US14148500
公开号:
US09464116B2
申请日:
2014.01.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
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