(E) the horse Come Suan Which of-N- { 4- [the chloro- 4- of 3- (2- pyridinyl methoxy) anilino-] -3- cyano -7- ethyoxyl -6- quinolyl } -4- (dimethylamino) -2- crotonamide is Ji Qi Knot crystalline form
The compound of method He You Off of the bright horse Come Suan Which form System Prepare Knot crystalline substance horse Come Suan Which form for being related to (E)-N- { 4- [the chloro- 4- of 3- (2- pyridinyl methoxy) anilino-] -3- cyano -7- ethyoxyl -6- quinolyl } -4- (dimethylamino) -2- crotonamide of this Hair, and the Drug Wu Group comprising its Men close object. The horse Come acid Which can control Treatment cancer with what, spy Do is by the raw Long of table skin because son is by those of Body family kinase shadow Ring cancer.本發明涉及(E)-N-{4-[3-氯-4-(2-吡啶基甲氧基)苯胺基]-3-氰基-7-乙氧基-6-喹啉基}-4-(二甲基氨基)-2-丁烯酰胺的馬來酸鹽形式，製備結晶馬來酸鹽形式的方法，和有關的化合物，以及包含它們的藥物組合物。所述馬來酸鹽可用於治療癌、特別是受表皮生長因子受體家族激酶影響的那些癌。
