The The of this Hair Ming Shi Off what following general formula replaces Yellow purine, wherein R1 to R3 is as Right benefit requires Zhong to Ding Righteousness, its mutual Change Iso Agencies Body, Li Body Iso Agencies Body, mixture, Qian Body Drug object are Ji Qi Which, its Drug Li Learn Quality , Te Do with You Price value is the active inhibiting effect of Right what enzyme dipeptidyl peptidase-IV.本發明是關於以下通式的經取代的黃嘌呤,其中R1至R3均如權利要求中定義,其互變異構體、立體異構體、混合物、前體藥物及其鹽,其具有有價值的藥理學性質,特別是對於酶二肽基肽酶-IV的活性的抑制作用。