The present invention relates to a new use of alisol and its derivative, which is extracted from water plantain for application of preparing medicine of hormone disorder disease treatment. In the present invention, the alisol and its derivative can be used as Androgen receptor (AR) agonist, Glucocorticoid receptor (GR) antagonists, Progesterone receptor (PR) antagonists, and Farnesoid X receptor (FXR) agonist, and can be applied for treatment of diabetes, endometriosis, uterine myoma, breast cancer, and diseases caused by androgen deficiency, and may be applied for preparation of pharmaceutical compositions for treatment of diabetes, endometriosis, uterine myoma, breast cancer, and diseases caused by androgen deficiency.本發明係關於一種澤瀉醇及其衍生物之新用途,係萃取自澤瀉,而用於製備治療激素失調疾病之藥物的應用。本發明中,該澤瀉醇及其衍生物可作為雄性素受體(AR)促效劑、糖皮質激素受體(GR)拮抗劑、黃體素受體(PR)拮抗劑與膽酸受體(FXR)促效劑。可應用於治療糖尿病、子宮內膜異位、子宮肌瘤、乳癌以及因雄性素缺乏導致之疾病,並可應用於製備治療糖尿病、子宮內膜異位、子宮肌瘤、乳癌以及因雄性素缺乏導致之疾病之醫藥組合物。
