Derivatives of hydroxy - 17 - 17 - pentafluoroetil estra - 4, 9 (10) - dien - 11 - aryl, processes for their Preparation and their use for the treatment of diseases
WOLFGANG SCHWEDE,ULRICH KLAR,CARSTEN MOLLER,ANDREA ROTGERI,WILHELM BONE
申请号：
HN2012000137
公开号：
HN2012000137A
申请日:
2012.01.20
申请国别(地区):
HN
年份:
2015
代理人:
摘要：
The Invention relates to Derivatives of hydroxy - 17 - 17 - pentafluoroetil estra - 49 (10) - dien - 11 - aryl of formula I with antagonistic Action of progesterone and processes for their preparation, their use for the Treatment or prevention of diseasesAs well as its use for the preparation of medicaments for the treatment and / or prevention of diseases, in particular (fibroids, uterine fibroids, endometriosis, uterine leiomyomas)Severe menstrual Bleeding, meningiomas, Hormone dependent Breast carcinomas and disorders associated with Menopause or to control Fertility and contraception in case of emergency.LA INVENCION SE REVIERE A DERIVADOS DE 17 - HIDROXI - 17 - PENTAFLUOROETIL - ESTRA - 4, 9(10) - DIEN - 11 - ARILO DE LA FORMULA I CON ACCION ANTAGONISTA DE PROGESTERONA Y PROCEDIMIENTOS PARA SU PREPARACION, A SU USO PARA EL TRATAMIENTO Y/O LA PREVENCION DE ENFERMEDADES, ASI COMO A SU USO PARA LA PREPARACION DE MEDICAMENTOS PARA EL TRATAMIENTO Y/O LA PREVENCION DE ENFERMEDADES, EN ESPECIAL DE FIBROIDES UTERINOS (MIOMAS, LEIOMIOMAS UTERINOS), DE ENDOMETRIOSIS, SANGRADOS MENSTRUALES SEVEROS, MENINGIOMAS, CARCINOMAS DE MAMA HORMONODEPENDIENTES Y DE TRASTORNOS ASOCIADOS CON LA MENOPAUSIA O PARA CONTROL DE FERTILIDAD Y ANTICONCEPCION EN CASO DE EMERGENCIA.
