In one embodiment, a device for extracting unwanted material in a vascular conduit of a subject is provided, including an elongate member having a proximal end and a distal end, for introduction into a vascular conduit of a subject. A material engaging structure is disposed on the elongate member, and is configured to expand to contact an inner surface of the vascular conduit to fragment and/or detach unwanted material in the conduit. The material engaging structure includes a contacting structure disposed on and rotatable about the elongate member, at least a first stripping member, having a first end and a second end, wherein the first end is associated with the elongate member and the second end is associated with the contacting structure, and a netting structure configured to collect and remove the unwanted material from the vascular conduit.
