Jiangsu Hengrui Medicine Co., Ltd.;Shanghai Hengrui Pharmaceutical Co., Ltd
发明人:
申请号:
EP18886827.7
公开号:
EP3722286A1
申请日:
2018.12.05
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention provides a salt of a phenylpropionamide derivative and a preparation method therefor. The present invention specifically provides an acetate, hydrochloride, phosphate, citrate, benzoate, or fumarate of 4-amino-1-((2R,5R,8R,14R)-2-(4-aminobutyl)-8-benzyl-5-isobutyl-4,7,10-trioxo-14-phenyl-3,6,9,12-tetraazapentadecan-1-acyl)piperidine-4-carboxylic acid, and a preparation method therefor. The salt of the compound of formula (I) of the present invention has good stability, and the simple process thereof facilitates easy operation. The invention is better suited for clinical treatment.