Oregon Health & Science University;The Government of the United States of America, dba The Department of Veterans Affairs
发明人:
David M. Lewinsohn,Deborah A. Lewinsohn
申请号：
US13719124
公开号：
US09040233B2
申请日:
2012.12.18
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods can also include detecting Mtb polypeptides and polynucleotides. Reagents for the detection of an Mtb infection are also disclosed.
