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METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION
专利权人:
OREGON HEALTH & SCIENCE UNIVERSITY;THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人:
David M. Lewinsohn,Deborah A. Lewinsohn
申请号:
US14856352
公开号:
US20160103127A1
申请日:
2015.09.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.
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