BAE YONG SOO,HONG SEUNG HO,KIM YOUNG HOON,HAN SEUNG SOO,KIM JIN
申请号:
IN1371DEN2015
公开号:
IN1371DEN2015A
申请日:
2015.02.19
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to IFN a fusion protein in which a cytoplasmic transduction peptide (CTP) and polyethylene glycol (PEG) are bonded to an IFN a protein. The IFN a fusion protein of the present invention is characterized in that the specific activity of interferon remains high the half life of the INF a fusion protein is extended when delivered in vivo and the mobility of the interferon in a liver is improved. The IFN a fusion protein of the present invention can be used in the development of protein drugs effective in preventing or treating liver diseases including various types of viral infections or the like.