UTAH-INHA DDS & ADVANCED THERAPEUTICS RESEARCH CENTER
发明人:
LEE, Eun Hye,이은혜,MAENG, Jin Hee,맹진희,KIM, Keun Su,김근수,LEE, Don Haeng,이돈행,PARK, Young Hwan,박영환
申请号：
KRKR2014/012265
公开号：
WO2015/088275A1
申请日:
2014.12.12
申请国别(地区):
WO
年份:
2015
代理人:
摘要：
The present invention provides a biodegradable medical adhesive or a sealant composition containing an oxidized glycosaminoglycan and a polyamine. The composition of the present invention exhibits improved effects in biodegradation, coating property, gelation time, hemostatic capacity, adhesive force, moisture absorptive capacity and the like, and thus can be applied to various medical uses in which a medical adhesive or sealant can be used, such as biotissue adhesion, filling, coating, adhesion prevention, wound coating, leakage prevention and hemostasis.La présente invention concerne une composition détanchéité ou adhésive médicale biodégradable contenant un glycosaminoglycane oxydé et une polyamine. La composition de la présente invention présente une amélioration des effets en termes de biodégradation, de propriété de revêtement, de temps de prise en gel, de capacité hémostatique, de force adhésive, de capacité dabsorption de lhumidité et similaire, et convient donc à diverses applications médicales utilisant un adhésif ou un colmatant, comme ladhérence dun tissu biologique, le remplissage, le revêtement, la prévention des adhérences, le revêtement des plaies, la prévention des fuites et lhémostase.본 발명은 산화 글리코사미노글리칸과 폴리아민을 포함하는 생분해성 의료용 접착제 또는 실란트 조성물을 제공한다. 본 발명의 조성물은 생분해성, 도포성, 겔화 시간, 지혈능, 접착력 및 수분 흡수력 등에서 개선된 효과를 나타내어, 생체 조직의 접착, 충전, 도포, 유착 방지, 창상 피복, 누출방지 및 지혈 등 의료용 접착제 또는 실란트가 사용 가능한 다양한 의료 용도로 활용될 수 있다.
