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PREPARATIONS INJECTABLES DE DICLOFENAC ET SELS ACCEPTABLES SUR LE PLAN PHARMACEUTIQUE DE CELUI-CI
专利权人:
TROIKAA PHARMACEUTICALS LTD
发明人:
PATEL, KETAN RAJNIBHAI,PATEL, MILAN RAJNIBHAI
申请号:
CA2596031
公开号:
CA2596031C
申请日:
2006.01.30
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention provides injectable formulations of water-soluble saltsof diclofenac in single doses of less than 2 ml, which cause significantlyless pain at the site of injection and can be administered by intradeltoidroute, in addition to intragluteal and slow intravenous route. Morespecifically the injectable preparations contain 75 mg to 100 mg of water-soluble salts of diclofenac, in about 1 ml injection solution withoutsignificantly raising the viscosity of the injection solution without the usesurfactants. The formulations are adjusted to pH 6 to 10 containing up to100mg of diclofenac salt in a medium comprising of water, along with one ormore co-solvent(s) / solubiliser(s), antioxidants, preservatives, buffers,alkali and stabilizers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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