エリスロポエチン徐放製剤とその作製方法
- 专利权人:
- 独立行政法人物質・材料研究機構
- 发明人:
- 生駒 俊之,利根川 亨,田中 順三,安居院 高志,長崎 健一,伊藤 茂男,梅村 孝司
- 申请号：
- JP2007315307
- 公开号：
- JP5352993B2
- 申请日:
- 2007.12.05
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To control the initial burst, and to make an apatite sustained release preparation of erythropoietin effective over a long period of time.
SOLUTION: A ceramic sustained release preparation is prepared by covering the surface of porous microparticles supporting a drug ingredient which is a physiologically active substance of different amino acid compositions having erythropoietin or an erythropoietin derivative-like physiological activity, and composed of an aggregation structure of metal ion-containing apatite nano-crystals having &le40 &mum average particle diameter, with a biodegradable polymer thin film.
COPYRIGHT: (C)2009,JPO&INPIT
- 来源网站：
- 中国工程科技知识中心
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