A toothbrush cleaning solution in which vinegar or alcohol is mixed with ethanol is provided. The toothbrush cleaning solution comprises 40-60% of ethanol, 20-40% of vinegar, 5-15% of licorice solution, 3-7% of pigment, and 3-7% of plum liquid. The toothbrush cleaning solution prevents diseases such as gum disease and periodontitis by eliminating bacteria present in the brush head and also allows a refreshing brushing.COPYRIGHT KIPO 2014에탄올에 식초 또는 주류알콜이 혼합된 칫솔 세정액이 제공된다. 이러한 칫솔 세정액은 칫솔모에 존재하는 세균을 제거하여 풍치, 치주염과 같은 병의 유발을 방지하고, 상쾌한 칫솔질이 가능하도록 한다.