Methods of using hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide
Guenter Linz;Peter Sieger;Gerd F. Kraemer;Matthias Hoffmann
发明人:
Guenter Linz,Peter Sieger,Gerd F. Kraemer,Matthias Hoffmann
申请号：
US12478178
公开号：
US08202867B2
申请日:
2009.06.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are hydrates and polymorphs of 4- [[(7R)-8-cyclopentyl-7 -ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide:as well as, processes for preparing them and their use as pharmaceutical compositions with antiproliferative activity.
