FISCHETTI, VINCENT A.,SCHMITZ, JONATHAN,GILMER, DANIEL,EULER, CHAD
申请号:
CA2833409
公开号:
CA2833409A1
申请日:
2012.04.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.